Cooking pork tenderloin in the oven at 400°F (about 204°C) typically takes about 20 to 25 minutes per pound (about 0.45 kg). Here's a general guideline for cooking pork tenderloin in the oven at 400°F:
1. **Preparation:** Preheat your oven to 400°F (about 204°C). While the oven is preheating, you can prepare the pork tenderloin by trimming any excess fat and seasoning it with your preferred herbs, spices, or marinade.
2. **Searing (Optional):** To add extra flavor and texture to the pork tenderloin, you can sear it in a hot skillet on the stovetop before transferring it to the oven. Sear the pork tenderloin on all sides until browned, about 2 to 3 minutes per side.
3. **Baking:** Place the seasoned or seared pork tenderloin on a roasting pan or baking sheet lined with parchment paper. Place the pan in the preheated oven.
4. **Cooking Time:** Bake the pork tenderloin in the oven for about 20 to 25 minutes per pound (about 0.45 kg), or until it reaches an internal temperature of 145°F (about 63°C) when measured with a meat thermometer inserted into the thickest part of the tenderloin.
5. **Resting:** Once the pork tenderloin reaches the desired internal temperature, remove it from the oven and let it rest for about 5 to 10 minutes before slicing. This allows the juices to redistribute throughout the meat, resulting in juicier and more flavorful pork tenderloin.
It's essential to use a meat thermometer to ensure that the pork tenderloin is cooked to a safe internal temperature of 145°F (about 63°C) to prevent foodborne illness. Additionally, cooking times may vary depending on the size and thickness of the pork tenderloin, so it's always a good idea to check for doneness using a meat thermometer.