The number of shots in a 750ml bottle depends on the size of the shot.
A standard shot in the United States is typically around 1.5 fluid ounces.
So, to find out how many shots are in a 750ml bottle:
750ml / 1.5 fl oz per shot = 500 shots
Therefore, there are approximately 500 shots in a 750ml bottle if each shot is 1.5 fluid ounces.